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Cribphilia The Pathogenesis and Behavioral Root Cause of Obsessive Compulsive Disorder

Table of Contents

OCD in Females and Correlation with Estradiol

First, brain tryptophan is converted to 5-hydroxytryptophan by the tryptophan hydroxylase enzyme (the rate-limiting step of serotonin synthesis). Second, 5-hydroxytryptophan is converted to serotonin by the aromatic amino acid decarboxylase enzyme. Therefore females with postpartum low Estrogen(after child delivery) stress develops OCD traits, and if not addressed with purpose, they become cribphillic, and then later progress towards allergic disorder, and later close to their perimenopausal age, develops autoimmunity.

Estrogen in females modulates Tryptophan which then gets synthesized into Serotonin.
Estrogen modulates Serotonin synthesis

Why men with OCD develops Non-emotional Sex?

It is very interesting to know here that even males have Estrogen, the way females have testosterone.

Men's Estrogen Remains high from erection, to up to two hours of Ejaculation, during which Estrogen synthesizes Serotonin
Men’s Estrogen Remains high from erection, to up to two hours of Ejaculation, during which Estrogen synthesizes Serotonin

Because OCD individuals have less amount of Estrogen, they need sex to produce the whatever little Estrogen and therefore Serotonin they can produce. Intimacy in men is modulated by Estrogen-Serotonin pathway, and not a function of Testosterone as Youtube and Whatsapp university may want you to believe.

Horses with Low Estrogen Develops OCD

In Hormone Replacement Therapy in the females, the Estrogen patches are created from the hormone from the horses. Horses are the animals with perhaps one of the highest Estrogen density. In the ancient times, when men used to fight wars on the horses, often it is observed that after the death of the warrior, his mare or the horse would die and vice versa.

Alexender died within a year after becoming depressed when his horse Bucephalus died in the conquest of India.

Why Love Failure Leads to OCD?

It is also important to know that estrogen markedly increases oxytocin binding in the ventromedial nucleus of the hypothalamus and infusion of oxytocin in this brain area increases female sexual behavior. Because Oxytocin also modulates male social behavior and is responsible for the mirror neuron activation, that enables us to physiologically couple with another individual, creating the human bond, loss of a human bond reduces Oxytocin, which further reduces Estrogen pathways, which increases OCD.

Because love is one of the strongest human bonds, detachment with the lover lowers Oxytocin, which in turn lowers Estrogen production, which in turn lowers Serotonin synthesis and reception, which in turn creates a tremendous stress, which is life-threatning, and because of this stress, individuals become cribphillic as a defense mechanism and thereafter progress towards OCD.

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